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Over the years I have written a number of books, more than have been published. I have never written a book because a publisher has suggested that I do so; all my books are based on ideas that I have had and submitted to a publisher, with the book largely formed, if not complete. Normally, I work on multiple projects simultaneously, sometimes for many years. The longest running project I have dates from 1986 and will be complete in 2010 and ready to be turned into a book and other media. The books listed below are those that are complete, which will be offered to publishers when it seems appropriate. I have included excerpts from each of these books, an introduction or possibly chapters and a conclusion. As time passes, if there is interest, I may post additional material that relates to each book.
In the case of the photo/story books such as The Golden Age Of Jazz, I plan to post individual photographs and stories on a regular basis until the complete book is available on line. I will follow this with similar projects involving celebrity portraits and other selected subjects.
Despite considerable recent experimentation in animal models and human volunteers, information on the central pathways of erection remains cursory at best.18 It is known that androgens play a predominantly modulating role by their effect on libido and sexual behaviour. Testosterone enhances sexual interest and the frequency of sexual acts; it increases the frequency of nocturnal erections but does not effect reflexogenic or psychogenic erections.19
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Improve muscle tone and strength.
Permanently alters or may injure erection bodies
Depression and anxiety: Psychological factors may be responsible for erectile dysfunction. These factors include stress, anxiety, guilt, depression, low self-esteem, and fear of sexual failure. For more information, please visit the Depression Center.
Depending on the cause of a man's ED, treatment can be quick, like Viagra, or take longer, like getting high blood pressure under control. It may even take a while to convince him to see a doctor at all.
The mean IIEF GS at Visit 1 was 25.7 (median 22, range 5 – 64), at Visit 3, 56.9 (median 62, range 7 – 73) and at Visit 4, 59.3 (median 60, range 18 – 73). The respective mean IIEF EDS was 8.2 (median 6, range 0 – 28), 23.5 (median 27, range 1 – 30) and 25.2 (median 25, range 6 – 30). There was no correlation between age and response to Viagra, although older men had relatively lower IIEF scores.
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Other side effects with Uprima® (9) include headache, dizziness, and flushing.
Neither age, ethnicity, obesity, nor tobacco use had any significant effect on the likelihood of the link between the two conditions.
In experiments with mice, researchers showed that Viagra (sildenafil) improved heart performance by preventing the breakdown of a compound called cGMP, which relaxes smooth muscle.
Venous leak: If the veins in the penis cannot prevent blood from leaving the penis during an erection, an erection cannot be maintained. This is known as a venous leak, and can be a result of injury or disease.
Steven G. Hentges of the American Chemistry Council, which represents the chemical industry, said the new study has little meaning for consumers. "Although this study presents interesting information, it has little relevance to average consumers who are exposed to trace levels of BPA," he said.
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Footnotes ?1 Abbreviations: PDE, phosphodiesterase; cAMP, adenosine 3?5?-cyclic monophosphate; cGMP, guanosine 3?5?-cyclic monophosphate; GAF, cyclic GMP, adenylyl cyclase, FhlA; CaM, calmodulin; PK, protein kinase; PKA, cAMP-dependent protein kinase; PKG, cGMP-dependent protein kinase; CNS, central nervous system; ANP, atrial natriuretic peptide; NO, nitric oxide; PDP, 9-(6-phenyl-2-oxohex-3-yl)-2-(3,4-dimethoxybenzyl)-purin-6-one; BAY 60-7750, 2-(3,4-dimethoxybenzyl)-7-[(1R)-1-hydroxyethyl]-4-phenylbutyl]-5-methylimidazo[5,1-f] [1,2,4]triazin-4(3H)-one; PI3K, phosphatidylinositol 3-kinase; IGF1, insulin-like growth factor 1; OPC-33450, 6-[3-[3-cyclooctyl-3-[(1R*,2R*)-2-hydroxycyclohexyl]ureido]-propoxy]-2(1H)-quinolinone; UCR, upstream conserved region; CRE, cAMP-responsive element-binding protein; RACK, receptor for activated C-kinase 1; AKAP, A-kinase anchoring proteins; ERK, extracellular signal-regulated kinase; BRL 50481, 3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene; PAS, Period, Arnt, and Sim; IBMX, 3-isobutyl-1-methylxanthine; BAY 73-6691, 1-(2-chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidine-4-one.
Above all, if taking over-the-counter supplements, be sure your doctor is informed before combining with prescription drugs he may recommend.
Article, publication date, and citation information can be found at http://pharmrev.aspetjournals.org.
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